Transcription factors and CD4 T cells seeking identity: masters, minions, setters and spikers
نویسندگان
چکیده
منابع مشابه
MiR-9-5p and miR-106a-5p dysregulated in CD4+ T-cells of multiple sclerosis patients and targeted essential factors of T helper17/regulatory T-cells differentiation
Objective(s): Multiple sclerosis (MS) is considered as a chronic type of an inflammatory disease characterized by loss of myelin of CNS.Recent evidence indicates that Interleukin 17 (IL-17)-producing T helper cells (Th17 cells) population are increased and regulatory T cells (Treg cells) are decreased in MS. Despite extensive research in understanding the mechanism of Th17 and Treg differentiat...
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Background: Polycystic ovary syndrome (PCOS) is considered as the most common cause of female infertility that affects 4-10% of women in the reproductive age. Previous studies have shown the role of a balanced immune response in a successful pregnancy and fertility. Objective: To investigate the T helper cells type 1 (Th1) /Th2/Th17/Treg paradigms in peripheral blood of infertile PCOS compared ...
متن کاملeffect of all-trans retinoic acid (atra) on viability, proliferation, activation and lineage-specific transcription factors of cd4+ t cells
all-trans retinoic acid (atra), as an active metabolite of vitamin a, has been shown to affect immune cells. this study was performed to evaluate the effect of atra on viability, proliferation, activation and lineage-specific transcription factors of cd4+ t cells. cd4+ t cells were separated from heparinized blood of healthy donors and were cultured in conditions, some with, some wit...
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: در تحقیقی که پیش روی دارید ابتدا سعی شده است که نقش میزان بهره مندی مدرسان زبان انگلیسی از سرمایه های فرهنگی و اجتماعی در چارچوب نظریه بوردیو(1986) بر میزان وابستگی آن ها به فرهنگ خودی بررسی شود. لذا دو پرسشنامه به طورهمزمان بین 342 مدرس زبان انگلیسی در بیش از 25 موسسه ی خصوصی زبان انگلیسی در سطح شهر مشهد توزیع شد. رابطه ی بین میزان دسترسی به سرمایه فرهنگی و اجتماعی و وابستگی به فرهنگ خودی از...
15 صفحه اولThe Effect of Beta Interferon on Dendritic Cells and Cytokine Synthesis by CD4+ T Cells
Background: Dendritic cells (DC) are a key regulator of the immune response, and interferon- beta (IFN-β) is considered an immunomodulatory molecule for DC. Objective: The purpose of this study was to evaluate the ability of IFN-β treated DC to induce cytokine secretion by CD4+ T cells. Methods: Dendritic cells were generated from blood monocytes with granulocyte-monocyte colony-stimulating fac...
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ژورنال
عنوان ژورنال: Immunology
سال: 2013
ISSN: 0019-2805
DOI: 10.1111/imm.12113